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KMID : 1161420190220020109
Journal of Medicinal Food
2019 Volume.22 No. 2 p.109 ~ p.120
Recent Progress in the Discovery of Bioactive Components from Edible Natural Sources with Antithrombotic Activity
Hahn Dong-Yup

Bae Jong-Sup
Abstract
Cardiovascular disease (CVD)-associated thrombosis are the most threatening cause of death worldwide. To resolve this crisis, efforts must be made to discover antithrombotic compounds for development of therapeutic agents with novel mechanisms of action, higher efficacy, and less adverse effects. It might also impact on the development of nutraceuticals to ameliorate vascular disease, and the development of appropriate diets to prevent CVDs. Recently, the research on antithrombotic compounds from edible natural sources increased swiftly by demand, and there has been remarkable progress. This review article covers bioactive components with antithrombotic activity that have been investigated in recent 5 years, more focused on the chemical structure classification (phenolics, polysaccharides, peptides, terpenes, and so on) and their original natural sources (traditional medicines, plants, animals, and foods).
KEYWORD
antithrombotic, cardiovascular diseases, edible natural sources, natural products, nutraceuticals, thrombosis
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